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2020

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2019

G.G. Yamoah et al., “Data Curation for Preclinical and Clinical Multimodal Imaging Studies” Mol Imaging Biol. 2019 Mar; doi: 10.1007/s11307-019-01339-0. pmid: 30868426
M. Kamal et al., “Bone regeneration in rabbit calvarial critical-sized defects filled with composite in situ formed xenogenic dentin and biphasic tricalcium phosphate/hyroxyapatite mixture” J Biomed Mater Res B Appl Biomater. 2019 Apr; 107(3):773-782. doi: 10.1002/jbm.b.34171. pmid: 30253039
J. Kalder et al., “New Large Animal Model for Aortic Aneurysms in the Viscerorenal Segment” J Surg Res. 2019 Mar; 240:156-164. doi: 10.1016/j.jss.2019.02.054. pmid: 30933829
M. Herrmann et al., “Luminal Calcification of the Microvasculature in Fetuin-A Deficient Mice Leads to Premature Aging and Death” bioRxiv, 2019 Mar; doi: 10.1101/577098
M. Bartneck et al. “The CCR2D Macrophage Subset Promotes Pathogenic Angiogenesis for Tumor Vascularization in Fibrotic Livers” Cell Mol Gastroenterol Hepatol. 2019;7(2):371-390. doi: 10.1016/j.jcmgh.2018.10.007. pmid: 30704985
C. Ergen et al., “Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo” Biomaterials. 2019 Jun; 206:49-60. doi: 10.1016/j.biomaterials.2019.03.025. pmid: 30925288
O. Bahlmann et al., “Altered laryngeal morphology in Period1 deficient mice”Ann Anat. 2019 May; 223:43-48. doi: 10.1016/j.aanat.2019.01.009. pmid: 30716467
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M. Erdem et al.,“Macrophages protect against loss of adipose tissue during cancer cachexia“. J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1128-1142. doi: 10.1002/jcsm.12450. PMID: 31318182.
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M. Freese et al., "Bone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eels”. Proc Natl Acad Sci U S A. 2019 Jun;116(23):11339-44. doi:10.1073/pnas.1817738116. pmid:31085642
M. Hofman et al., "Effect of neurokinin-1-receptor blockage on fracture healing in rats”. Sci Rep. 2019 Jul;9(1):9744. doi:10.1038/s41598-019-46278-6. pmid:31278316
E. Fiegle et al., "Dual CTLA-4 and PD-L1 Blockade Inhibits Tumor Growth and Liver Metastasis in a Highly Aggressive Orthotopic Mouse Model of Colon Cancer”. Neoplasia. 2019 Sep;21(9):932-44. doi:10.1016/j.neo.2019.07.006. pmid:31412307
F. Wolf et al., "MR and PET-CT monitoring of tissue-engineered vascular grafts in the ovine carotid artery”. Biomaterials. 2019 Sep;216:119228. doi:10.1016/j.biomaterials.2019.119228. pmid:31195299
L. Frintrop et al., "The reduction of astrocytes and brain volume loss in anorexia nervosa-the impact of starvation and refeeding in a rodent model". Transl Psychiatry. 2019 Jun;9(1):159. doi:10.1038/s41398-019-0493-7. pmid:31164627
Q. Sun et al., "Elastin imaging enables noninvasive staging and treatment monitoring of kidney fibrosis”. Sci Transl Med. 2019 Apr;11(486):eaat4865. doi:10.1126/scitranslmed.aat4865. pmid:30944168
S. Kunjachan et al., “Selective priming of tumor Blood Vessels by Radiation therapy enhances nanodrug Delivery”. Sci Rep. 2019 Nov.;9(1):1-4. doi:10.1038/s41598-019-50538-w.

2018

S. Rosenhain et al., “A preclinical micro-computed tomography database including 3D whole body organ segmentations” Sci Data. 2018 Dec; 5:180294. doi: 10.1038/sdata.2018.294. pmid: 30561432
S. Yasmin-Karim et al., “Radiation and Local Anti-CD40 Generate an Effective in situ Vaccine in Preclinical Models of Pancreatic Cancer” Front Immunol. 2018 Sep; 9:2030. doi: 10.3389/fimmu.2018.02030. pmid: 30245691
M. Kamal et al., “Comparison of Bone Grafts From Various Donor” J Craniofac Surg. 2018 Sep; (6):1661-1665. doi: 10.1097/SCS.0000000000004586. pmid: 29762319
B. Theek et al., “Histidine-rich glycoprotein-induced vascular normalization improves EPR-mediated drug targeting to and into tumors” J Control Release. 2018 Jul; 282:25-34. doi: 10.1016/j.jconrel.2018.05.002. pmid: 29730154
K.T. Warzecha et al., “Targeting and Modulation of Liver Myeloid Immune Cells by Hard-Shell Microbubbles” Adv Biosyst. 2018 May; doi: 10.1002/adbi.201800002. pmid: 29876517
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2017

M. Kamal et al., “Bone regeneration using composite non-demineralized xenogenic dentin with beta-tricalcium phosphate in experimental alveolar cleft repair in a rabbit model” J Transl Med, vol. 15, no. 1, p. 263, 2017 Dec. doi: 10.1186/s12967-017-1369-3 pmid: 29274638
L. J. Brylka et al., “Post-weaning epiphysiolysis causes distal femur dysplasia and foreshortened hindlimbs in fetuin-A-deficient mice” PLoS One. 2017 Oct;12(10). doi: 10.1371/journal.pone.0187030. pmid: 29088242
J.-M. Bangen et al., “Targeting CCl4 -induced liver fibrosis by RNA interference-mediated inhibition of cyclin E1 in mice” Hepatology, vol. 66, no. 4, pp. 1242–1257, 2017 Oct. doi: 10.1002/hep.29275. pmid: 28520165
J. G. Mannheim et al., “Standardization of Small Animal Imaging-Current Status and Future Prospects” Mol Imaging Biol, 2017 Oct. doi:10.1007/s11307-017-1126-2. pmid: 28971332
C. Hage et al., “Comparison of the Accuracy of FMT/CT and PET/MRI for the Assessment of Antibody Biodistribution in Squamous Cell Carcinoma Xenografts” J. Nucl. Med., 2017 Aug; vol. 59 no. 1 44-50. doi: 10.2967/jnumed.117.197178. pmid: 28848038
P. K. Srinivasan et al., “Novel synthetic adhesive as an effective alternative to Fibrin based adhesives” World J Hepatol, vol. 9, no. 24, pp. 1030–1039, 2017 Aug. doi: 10.4254/wjh.v9.i24.1030. pmid: 28932349
Y. Tsvetkova et al., “Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers” Nano Lett., 17 (8), pp 4665–4674, 2017 Aug. doi: 10.1021/acs.nanolett.7b01171. pmid: 28715227
W. Al Rawashdeh et al., “Noninvasive Assessment of Elimination and Retention using CT-FMT and Kinetic Whole-body Modeling” Theranostics, vol. 7, no. 6, pp. 1499–1510, 2017 April. doi: 10.7150/thno.17263. pmid: 28529633
D. Bauerschlag et al., “Detection and Specific Elimination of EGFR+ Ovarian Cancer Cells Using a Near Infrared Photoimmunotheranostic Approach” Pharm. Res., vol. 34, no. 4, pp. 696–703, Apr. 2017. doi: 10.1007/s11095-017-2096-4. pmid: 28074431
M. Rose et al., “ITIH5 mediates epigenetic reprogramming of breast cancer cells” Mol. Cancer, vol. 16, no. 1, p. 44, Feb. 2017. doi: 10.1186/s12943-017-0610-2. pmid: 28231808
M. Kamal et al., “A rabbit model for experimental alveolar cleft grafting” J Transl Med, vol. 15, no. 1, p. 50, Feb. 2017. doi: 10.1186/s12967-017-1155-2. pmid: 28235419
C. Ergen et al., “Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles” Biomaterials, vol. 114, pp. 106–120, Jan. 2017. doi: 10.1016/j.biomaterials.2016.11.009. pmid: 27855336
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2016

S. Rosenhain et al., “Sensitivity and accuracy of hybrid fluorescence-mediated tomography in deep tissue regions” J Biophotonics, Nov. 2016. doi: 10.1038/sdata.2018.294. pmid: 30561432
N. Beztsinna et al., “Amphiphilic Phospholipid-Based Riboflavin Derivatives for Tumor Targeting Nanomedicines” Bioconjug. Chem., vol. 27, no. 9, pp. 2048–2061, Sep. 2016. doi: 10.1021/acs.bioconjchem.6b00317. pmid: 27412680
C. Adamzyk et al., “Bone tissue engineering using polyetherketoneketone scaffolds combined with autologous mesenchymal stem cells in a sheep calvarial defect model” J Craniomaxillofac Surg, vol. 44, no. 8, pp. 985–994, Aug. 2016. doi: 10.1016/j.jcms.2016.04.012. pmid: 27328894
C. Xie et al., “Visualization of Vascular and Parenchymal Regeneration after 70% Partial Hepatectomy in Normal Mice” J Vis Exp, no. 115, Sep. 2016. doi: 10.3791/53935. pmid: 27685096
C. Xie et al., “Quantification of Hepatic Vascular and Parenchymal Regeneration in Mice” PLoS ONE, vol. 11, no. 8, 2016 Aug. doi: 10.1371/journal.pone.0160581. pmid: 27494255
B. Theek et al., “Sonoporation enhances liposome accumulation and penetration in tumors with low EPR” J Control Release, vol. 231, pp. 77–85, Jun. 2016. doi: 10.1016/j.jconrel.2016.02.021. pmid: 26878973
W. Wei et al., “Intrahepatic Size Regulation in a Surgical Model: Liver Resection-Induced Liver Regeneration Counteracts the Local Atrophy following Simultaneous Portal Vein Ligation” Eur Surg Res, vol. 57, no. 1–2, pp. 125–137, Jun. 2016. doi: 10.1016/j.surg.2015.12.005. pmid: 26879073
J. Gautheron et al., “The necroptosis-inducing kinase RIPK3 dampens adipose tissue inflammation and glucose intolerance” Nat Commun, vol. 7, p. 11869, Jun. 2016. doi: 10.1038/ncomms11869. pmid: 27323669
W. Wei et al., “Establishment of a rat model: Associating liver partition with portal vein ligation for staged hepatectomy” Surgery, vol. 159, no. 5, pp. 1299–1307, May 2016. doi: 10.1016/j.surg.2015.12.005. pmid: 26879073
M. Bartneck et al., “Histidine-rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease” Hepatology, vol. 63, no. 4, pp. 1310–1324, Apr. 2016. doi: 10.1002/hep.28418. pmid: 26699087
D. Dziewiecki et al., “Osteoneogenesis due to periosteal elevation with degradable and nondegradable devices in Göttingen Minipigs” J Craniomaxillofac Surg, vol. 44, no. 3, pp. 318–324, Mar. 2016. doi: 10.1016/j.jcms.2015.12.011. pmid: 26810955
F. Gremse, et al., “GPU-Accelerated Adjoint Algorithmic Differentiation” Comput Phys Commun, vol. 200, pp. 300–311, Mar. 2016. doi: 10.1137/130948811. pmid: 26941443
S. C. Baetke et al., “Squamous Cell Carcinoma Xenografts: Use of VEGFR2-targeted Microbubbles for Combined Functional and Molecular US to Monitor Antiangiogenic Therapy Effects” Radiology, vol. 278, no. 2, pp. 430–440, Feb. 2016. doi: 10.1148/radiol.2015142899. pmid: 26313618
M. Brinkmann et al., “Micro-computed tomography (μCT) as a novel method in ecotoxicology–determination of morphometric and somatic data in rainbow trout (Oncorhynchus mykiss)” Sci. Total Environ., vol. 543, no. Pt A, pp. 135–139, Feb. 2016. doi: 10.1016/j.scitotenv.2015.11.020. pmid: 26580735
J. Ehling et al., “Quantitative Micro-Computed Tomography Imaging of Vascular Dysfunction in Progressive Kidney Diseases” J. Am. Soc. Nephrol., vol. 27, no. 2, pp. 520–532, Feb. 2016. doi: 10.1681/ASN.2015020204. pmid: 26195818
F. Gremse, et al., “Imalytics Preclinical: Interactive Analysis of Biomedical Volume Data” Theranostics, vol. 6, no. 3, pp. 328–341, Jan. 2016. doi: 10.3791/52770. pmid: 26066033

2015

C. Schürmann et al., “The NADPH oxidase Nox4 has anti-atherosclerotic functions” Eur. Heart J., vol. 36, no. 48, pp. 3447–3456, Dec. 2015. doi: 10.1371/journal.pone.0130374. pmid: 26086218
S. Akhtar et al., “Endothelial Hypoxia-Inducible Factor-1α Promotes Atherosclerosis and Monocyte Recruitment by Upregulating MicroRNA-19a” Hypertension, vol. 66, no. 6, pp. 1220–1226, Dec. 2015. doi: 10.1161/HYPERTENSIONAHA.115.05886. pmid: 26483345
H. Dähring et al., “Improved Hyperthermia Treatment of Tumors Under Consideration of Magnetic Nanoparticle Distribution Using Micro-CT Imaging“ Mol Imaging Biol, vol. 17, no. 6, pp. 763–769, Dec. 2015. doi: 10.1007/s11307-015-0848-2. pmid: 25896813
C. Sänger et al., “Intrahepatic Vascular Anatomy in Rats and Mice–Variations and Surgical Implications” PLoS ONE, vol. 10, no. 11, Nov 2015. doi: 10.1371/journal.pone.0141798. pmid: 26618494
Y. Shi et al., “Fluorophore labeling of core-crosslinked polymeric micelles for multimodal in vivo and ex vivo optical imaging” Nanomedicine (Lond), vol. 10, no. 7, pp. 1111–1125, 2015. doi: 10.2217/nnm.14.170. pmid: 25929568
F. Gremse et al., “Hybrid μCT-FMT imaging and image analysis” J Vis Exp, no. 100, Jun. 2015. doi: 10.3791/52770. pmid: 26066033
J. Domey et al., “Gold nanoparticles allow detection of early-stage edema in mice via computed tomography imaging” Int J Nanomedicine, vol. 10, pp. 3803–3814, Jun. 2015. doi: 10.2147/IJN.S77383. pmid: 26082631
C. Schürmann et al., “Micro-CT Technique Is Well Suited for Documentation of Remodeling Processes in Murine Carotid Arteries” PLoS ONE, vol. 10, no. 6, Jun. 2015. doi: 10.1371/journal.pone.0130374. pmid: 26086218
D. Doleschel et al., “Erythropoietin improves the accumulation and therapeutic effects of carboplatin by enhancing tumor vascularization and perfusion” Theranostics, vol. 5, no. 8, pp. 905–918, May 2015. doi: 10.7150/thno.11304. pmid: 26000061
S. Kossatz et al., “Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery” Breast Cancer Res., vol. 17, p. 66, May 2015. doi: 10.1186/s13058-015-0576-1. pmid: 25968050
Y. Shi et al., “Complete Regression of Xenograft Tumors upon Targeted Delivery of Paclitaxel via Π-Π Stacking Stabilized Polymeric Micelles” ACS Nano, vol. 9, no. 4, pp. 3740–3752, Apr. 2015. doi: 10.1021/acsnano.5b00929. pmid: 25831471
M. E. Mertens et al., “USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts“ Biomaterials, vol. 39, pp. 155–163, Jan. 2015. doi: 10.1016/j.biomaterials.2014.10.076. pmid: 25465443

2014

L. Novo et al., “Decationized polyplexes as stable and safe carrier systems for improved biodistribution in systemic gene therapy” J Control Release, vol. 195, pp. 162–175, Dec. 2014. doi: 10.1016/j.jconrel.2014.08.028. pmid: 25204289
A. Rix et al., “Influence of repetitive contrast agent injections on functional and molecular ultrasound measurements” Ultrasound Med Biol, vol. 40, no. 10, pp. 2468–2475, 2014 Oct. doi: 10.1016/j.ultrasmedbio.2014.04.010. pmid: 25023096
F. Fuge et al., “In-vivo detection of the erythropoietin receptor in tumours using positron emission tomography” Eur Radiol, 2014 Sep. doi: 10.1007/s00330-014-3413-5. pmid: 25196361
A. Assmann et al., “The degeneration of biological cardiovascular prostheses under pro-calcific metabolic conditions in a small animal model” Biomaterials, vol. 35, no. 26, pp. 7416–7428, 2014 Aug. doi: 10.1016/j.biomaterials.2014.05.034. pmid: 24917029
F. Gremse et al., “Absorption reconstruction improves biodistribution assessment of fluorescent nanoprobes using hybrid fluorescence-mediated tomography” Theranostics, vol. 4, no. 10, pp. 960–971, Jul 2014. doi: 10.7150/thno.9293. pmid: 25157277
F. Gremse et al., “Performance of lead-free versus lead-based hunting ammunition in ballistic soap” PLoS ONE, vol. 9, no. 7, Jul 2014. doi: 10.1371/journal.pone.0102015. pmid: 25029572
F. Duttenhoefer et al., “Magnetic resonance imaging in zirconia-based dental implantology” Clin Oral Implants Res, Jun 2014. doi: 10.1111/clr.12430. pmid: 24893967
B. Theek et al., “Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging” J Control Release, vol. 182, pp. 83–89, May 2014. doi: 10.1016/j.jconrel.2014.03.007. pmid: 24631862
A. Schober et al., “MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1” Nat. Med., vol. 20, no. 4, pp. 368–376, Apr 2014. doi: 10.1038/nm.3487. pmid: 24584117
W. Al Rawashdeh et al., “Optical tomography of MMP activity allows a sensitive noninvasive characterization of the invasiveness and angiogenesis of SCC xenografts” Neoplasia, vol. 16, no. 3, p. 235–246, 246.e1, Mar 2014. doi: 10.1016/j.neo.2014.03.005. pmid: 24784000
X. Li et al., “Activation of CXCR7 limits atherosclerosis and improves hyperlipidemia by increasing cholesterol uptake in adipose tissue” Circulation, vol. 129, no. 11, pp. 1244–1253, Mar 2014. doi: 10.1161/CIRCULATIONAHA.113.006840. pmid: 24374972
M. E. Mertens et al., “Iron Oxide-labeled Collagen Scaffolds for Non-invasive MR Imaging in Tissue Engineering” Adv Funct Mater, vol. 24, no. 6, pp. 754–762, Feb 2014. doi: 10.1002/adfm.201301275. pmid: 24569840
J. Ehling et al., “Micro-CT imaging of tumor angiogenesis: quantitative measures describing micromorphology and vascularization” Am. J. Pathol., vol. 184, no. 2, pp. 431–441, Feb 2014. doi: 10.1016/j.ajpath.2013.10.014. pmid: 24262753
J. Ehling et al., “CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis” Gut, Feb 2014. doi: 10.1136/gutjnl-2013-306294. pmid: 24561613
S. Kunjachan et al., “Passive versus active tumor targeting using RGD- and NGR-modified polymeric nanomedicines” Nano Lett., vol. 14, no. 2, pp. 972–981, Feb 2014. doi: 10.1021/nl404391r. pmid: 24422585

2013

S. Akhtar et al. “CXCL12 Promotes the Stabilization of Atherosclerotic Lesions Mediated by Smooth Muscle Progenitor Cells in Apoe-Deficient Mice“ Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):679-86. doi: 10.1161/ATVBAHA.112.301162. pmid: 23393393
L. Abou-Elkacem et al., “Regorafenib Inhibits Growth, Angiogenesis, and Metastasis in a Highly Aggressive, Orthotopic Colon Cancer Model.” Mol Cancer Ther. 2013 Jul;12(7):1322-31. doi: 10.1158/1535-7163.MCT-12-1162. pmid: 23619301
X. Li et al., “Activation of CXCR7 Limits Atherosclerosis and Improves Hyperlipidemia by Increasing Cholesterol Uptake in Adipose Tissue.” Circulation. 2014 Mar;129(11):1244-53. doi: 10.1161/CIRCULATIONAHA.113.006840. pmid: 24374972
S. Kunjachan et al., “Noninvasive optical imaging of nanomedicine biodistribution” ACS Nano, vol. 7, no. 1, pp. 252–262, Jan 2013. pmid: 23067565

2012

P. Paulsen et al., “Game Meat Hygiene in Focus” Wageningen Academic Publishers. 2012
D. Doleschel et al., “Targeted Near-Infrared Imaging of the Erythropoietin Receptor in Human Lung Cancer Xenografts” J Nucl Med. 2012 Feb;53(2):304-11. doi: 10.2967/jnumed.111.091124. Epub 2012 Jan 6.
M. Nazari-Jahantigh et al., “MicroRNA-155 promotes atherosclerosis by repressing Bcl6 in macrophages” J. Clin. Invest., vol. 122, no. 11, pp. 4190–4202, Nov. 2012.

2011

E. A. Liehn et al., “Double-Edged Role of the CXCL12/CXCR4 Axis
in Experimental Myocardial Infarction”J Am Coll Cardiol. 2011 Nov 29;58(23):2415-23. doi: 10.1016/j.jacc.2011.08.033.
W. Lederle et al., “Failure of annexin-based apoptosis imaging in
the assessment of antiangiogenic therapy effects.” EJNMMI Res. 2011 Nov 17;1(1):26. doi: 10.1186/2191-219X-1-26.
F.Gremse et al.,”Quantitative and qualitative Data analysis.” Small animal imaging. 2011
L. Abou-Elkacemet al., “Comparison of CT, MRI and optical reflectance imaging for assessing the growth of GFP/RFP- expressing tumors.”
“Comparison of CT, MRI and optical reflectance imaging for assessing the growth of GFP/RFP-expressing tumors.” Anticancer Res. 2011 Sep;31(9):2907-13
F. Gremse et al., “Virtual elastic sphere processing enables reproducible quantification of vessel stenosis at CT and MR angiography” Radiology, vol. 260, no. 3, pp. 709–717, Sep. 2011.

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